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Nanoscale Adv 4:52335244

10 SIDE EFFECTS ASSOCIATED WITH HYDROQUINONE Mild erythema Burning sensation Dryness Fissuring of paranasal and infraorbital areas Stinging Localized hypersensitivity Pruritus Scaling Exogenous ochronosis HYDROQUINONE WARNINGS Contains sodium metabisulfite which may cause an allergic-type reaction including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in susceptible people

Typical dosing protocols used in research settings have varied considerably, with reported ranges from 5-10 mg administered subcutaneously for periods of 10-20 days, often followed by several months without treatment

For skincare, both morning and evening have a rationale, and many routines use it twice a day